ProtiPrep™ hides a clever secret in its lid. Once the sample is loaded onto the spin column, the yellow lid is screwed on tightly and that single twist is all it takes. A built-in buffer compartment ruptures automatically, releasing a precisely metered buffer directly onto the column.
The result: guaranteed buffer consistency across every run, every user, every lab. No preparation the evening before. No variability from manually prepared buffers. No compromises on storage conditions. Just reliable, reproducible results straight out of the box.
Mass spectrometry offers exceptional sensitivity for proteomics research; however, its reliability is fundamentally dependent on the quality of sample preparation. Each stage from initial sample collection to the generation of peptide mixtures can introduce variability that impacts data quality and reproducibility (Ignjatovic et al., 2019). To mitigate these challenges, rigorous standards for sample collection and handling have been established. In addition, ready-to-use kits are now available for critical steps such as denaturation, reduction, alkylation, digestion, and peptide purification, ensuring consistent and dependable results throughout your workflow. The same principles apply to the depletion of abundant proteins. Rather than relying on labor-intensive manual protocols, pre-assembled, single-use depletion kits are increasingly favoured by researchers for their ability to:
At Amiprox, our solutions are engineered to deliver consistency, simplicity, and high performance at every stage of your proteomics workflow, empowering you to achieve reliable and reproducible results with confidence.
As the new wave of proteomics in diagnostics continues to rise, the demand for robust and reproducible sample preparation kits remains a key bottleneck. While ProtiPrep™ Pop2 has improved the discovery of low-abundance proteins in mass spectrometry, it is not ideally suited for high-throughput applications. To address this limitation, we developed ProtiPlate Pop2, which transfers the proven Pop2 chemistry into a 96-well format while maintaining the same formulation for efficient depletion of HSA and IgG from undiluted plasma samples. These deep-well plates are designed for processing large sample volumes, either manually or using liquid handling systems. Upcoming additions to the ProtiPlate line will extend high-throughput capabilities to antibody purification and broader depletion panels, supporting an expanding range of plasma proteomics workflows.
